Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured.
Tags: Aplastic Anemia, bone marrow disease | Category: Hematology, Pathophysiology | Posted at February 10, 2010 with 0 Comments
