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Pathophysiology Algorithm Diagram of Hypertensive Emergencies

Pathophysiology of hypertensive emergency (crisis hypertension) is shown in the picture below (click to enlarge image). Hypertensive emergency is characterized by a severe elevation in blood pressure (> 180/120 mm Hg) complicated by evidence of impending or progressive target organ dysfunction (coronary ischemia, disordered cerebral function, cerebrovascular events, pulmonary edema, and renal failure). …

Bone Marrow Failure Syndroms in the Pathophysiology Concept of Aplastic Anemia

aplastic-anemia-pathophysiology-diagram_thumb.jpg

Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured. Sections such Clinical associations, Pathophysiol…