A hypertonic saline and traumatic brain injury has a close interconnection between. As an osmotherapeutic agent, hypertonic saline may have been used as possible substitutes for early known agent – manitol. A suggested algorithm in the treatment of traumatic brain injury (TBI) as cerebral resuscitation is shown in below diagram. This algorithm covers normovolemia maintenance, seizure prophylaxis, artificial ventilation, ICP monitoring, Pa…




