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Bone Marrow Failure Syndroms in the Pathophysiology Concept of Aplastic Anemia

Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured.

Category: Hematology, Pathophysiology | Tags: , , | 9:21 am | comments 0 Comments

Understanding Cord Blood Stem Cell Transplantation

Stem cell transplantation used to perform in order to treat patients with some severe inherited or acquired disorders of the marrow or the immune system. The cord blood contains numbers of stem cells to be used in blood stem cell transplantation for certain patients. And herein a document that will provide a factsheet for understanding Cord Blood Stem Cell Transplantation.

Category: Internist | Tags: , , | 8:23 am | comments 0 Comments