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Pediatric Septic Shock Clinical Practice Guideline

This Clinical Practice Guideline for Pediatric Sepsis was authorized by Dr. Lennox Huang as the PCCN Clinical Practice Guideline for Septic Shock. A high suspicion for sepsis in children with abnormal vital signs is key to early recognition and treatment. Accordingly, the key principles of this guideline are Assess and manage ABCs according to PALS /ACCM guidelines, Early rapid fluid resuscitation, Inotropic therapy should be reserved for shoc…

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Understanding the Mechanisms and the Role of Glutathione in Lens Metabolism

Electrolyte disturbances which resulted an osmotic imbalances characterized the cataracts. It is important to understand the role glutatione and its enzime co-factors play in the metabolism within the lens. As seen in the figure below, glutathione is composed of the amino acids cysteine, glutamic acid, and glycine and its synthesis within the lens takes place in two steps. The description of this sections are clearly described in this document….