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The Life Cycle of Plasmodium falciparum in the Pathogenesis of Malaria

Malaria is a very old disease originating in Africa, spreading as humankind migrated to other lands. The disease gets its name from an Italian word for “bad air”. If we need to investigate the progress of malaria, we should consider the relationships between human and Anopheles mosquito populations, since both are necessary for the life cycle of Plasmodium. The diagram shows the life cycle of Plasmodium falciparum – the deadliest of all the hum…

Pediatric Septic Shock Clinical Practice Guideline

This Clinical Practice Guideline for Pediatric Sepsis was authorized by Dr. Lennox Huang as the PCCN Clinical Practice Guideline for Septic Shock. A high suspicion for sepsis in children with abnormal vital signs is key to early recognition and treatment. Accordingly, the key principles of this guideline are Assess and manage ABCs according to PALS /ACCM guidelines, Early rapid fluid resuscitation, Inotropic therapy should be reserved for shoc…