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Serum Calcium Concentration in the Pathophysiology of Hypoparathyroidism

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Hypoparathyroidism is deficiency of parathyroid hormone (PTH) which resulting in hypocalsemia and hyperphosphatemia. It involved calcium concentration which plays a vital role in the the pathophysiology and diagnosis of hypoparathyroidism. The following diagram shows the hydroxilation of vitamin D to its active form and its action to increase the serum calcium concentration. Find sections such the roles of PTH, vitamin D and calcitonin, detaile…

Children Sickle Cell Disease Management Guideline for Paediatrics Physician

The folowing physician guideline provides direction for the management of children with sickle cell disease who present to the emergency department with complications of their condition (Acute Painful Episodes, Fever, Acute Chest Syndrome or Pneumonia). You will be prensented with sections such General Recommendations for the Management of Paediatric Sickle Cell Disease, Guideline for Acute Painful Episode (Vaso Occlusive Disease), the manageme…