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A Physiopathological Mechanism for Postmenopausal Bone Loss in Osteoporotic Women

An imbalance between bone formation and bone resorption is thought to underlie the pathogenesis of reduced bone mass (bone loss) in osteoporosis. A study which evaluated a possibilities increase in spontaneous osteoclast formation in postmenopausal osteoporotic women is described below.   The schematic diagram demonstrates an increase in the production of RANKL and TNF-A by PBMC of osteoporotic women with respect to controls. This study al…

Category: Pathophysiology | Tags: , , , | 9:48 am | comments 0 Comments

Renin Angiotensin – Aldosteron Regulation System Diagram

thereninangiotensinsystemdiagram.png

The following diagram schemes the representation of the renin-angiotensin system showing its major components, the regulators of renin release and the primary effects of angiotensin II (AII) excluding the AII receptors. Renin may play a critical role in the pathogenesis of most hypertension. Complete review on Renin Angiotensin – Aldosteron Regulation System Diagram can be seen here (source: medind.nic.in). …

Category: Pathophysiology | Tags: , , | 9:53 am | comments 0 Comments