The factors involved in the pathogenesis of Cor Pulmonale in Chronic Obstructive Pulmonary Disease (COPD) can be seen in the following diagram. As seen in the pathogenesis of Cor Pulmonale diagram above, hypoxemia exerts an effect on the pulmonary vasculature separate from alveolar hypoxia, as does acidosis. The increased pulmonary vascular resistance is contibuted by the reduction in pulmonary capillary surface area caused by emphysema. Furthe…
The following guideline article contain materials related to evolving concept and new potential therapies of sepsis based on its pathophysiology and genetic basis for the host responses to the syndrome. This pathophysiology diagram shows the response of many immune cells including macrophages, dendritic cells and CD4 T Cells. You can find the explanations of sections such as mechanism of immune suppression in sepsis, reappraisal of Lewis Thoma…
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