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Bone Marrow Failure Syndroms in the Pathophysiology Concept of Aplastic Anemia

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Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured. Sections such Clinical associations, Pathophysiol…

Category: Hematology, Pathophysiology | Tags: , , | 9:21 am | comments 0 Comments

The Pathophysiology Diagram of Diabetic Ketoacidosis

One of type I diabetes is Diabetic Ketoacidosis (DKA). DKA can develop in a new-onset type I diabetic or a diabetic who misses insulin doses, poor insulin compliance and lack of knowledge about managing insulin administration in acute illness. The diagram below shows the pathophysiology diagram of DKA. Completed understanding of Pathophysiology, Clinical Presentation and Management of Adults with Diabetic Ketoacidosis, can be found in the foll…

Category: Pathophysiology | Tags: , , | 10:16 am | comments 0 Comments