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Activated Hepatic Stellate Cell Diagram in Liver Fibrosis Process

Liver fibrosis is a dynamic process resulting in excessive deposition of extracellular matrix (ECM) components. It is considered a common response to many chronic hepatic injuries which involves several cell types, cytokines, chemokines and growth factors leading to a disruption of homeostatic mechanisms that maintain the liver ecosystem. The picture shows you with diagram of activated hepatic stellate cell actions and interactions in liver fi…

Category: Endocrinologist, Pathophysiology | Tags: , , | 10:30 am | comments 0 Comments

Leukocytes and the Pathogenesis of Capillary Occlusion in Diabetic Retinopathy

Diabetic Retinopathy is retinopathy (damage to the retina) caused by complications of diabetes mellitus, which can eventually lead to blindness (wikipedia.org). The schematic diagram shows increased leukocyte endothelial cell adhesion and entrapment (leukostasis) in diabetic retinopathy. Completed role of leukocytes in the pathogenesis of capillary occlusion, and discussion about the potential of leukostasis as a new promising target in the tr…

Category: Ophthalmology, Pathophysiology | Tags: , , , | 11:26 am | comments 0 Comments