Cushing’s Syndrome (hypercortisolism) is hormonal disorder caused by prolonged exposure of the body’s tissues to high levels of the hormone cortisol which can be from both serum ACTH low (iatrogenic, adrenal neoplasm) and serum ACTH high (pituitary neoplasm, ectopic ACTH). The pathophysiology diagram of Cushing’s Syndrome can be understood through the above illustration, since the outcome of this cycle is people develop Cushing’s syndrome becau…



