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Cushing’s Syndrome Pathophysiology Diagram and Guideline

negative feedback servo mechanism diagram of Cushing's Syndrome

Cushing’s Syndrome (hypercortisolism) is hormonal disorder caused by prolonged exposure of the body’s tissues to high levels of the hormone cortisol which can be from both serum ACTH low (iatrogenic, adrenal neoplasm) and serum ACTH high (pituitary neoplasm, ectopic ACTH). The pathophysiology diagram of Cushing’s Syndrome can be understood through the above illustration, since the outcome of this cycle is people develop Cushing’s syndrome becau…

Acute Flaccid Paralysis (AFP) Cases WHO Classification System Diagram

The following schematic shows the WHO Classification System for Acute Flaccid Paralysis (AFP) Cases. All 3 types of poliovirus (Enterovirus types 1, 2, and 3) may cause the paralysis. 1. Adequate specimens means 2 specimens collected 24-48 hours apart and within 14 days of onset of paralysis. 2. The specimen arriving at the laboratory must be of adequate volume approximately 8-10 grams), have appropriate documentation (laboratory request form) a…