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Pathophysiology of Chronic Alcoholic Pancreatitis

Pancreatitis due to alcohol abuse is a very painful and potentially fatal condition. The following article reported the mechanisms of alcohol activating of signal transduction pathways related to the pathophysiology of chronic alcoholic pancreatitis. You’ll be described with oxidative and a non-oxidative pathway of the alcohol metabolism, genetic predisposition of acute and chronic pancreatitis, stimulatory effect on gastric acid secretio…

Serum Calcium Concentration in the Pathophysiology of Hypoparathyroidism

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Hypoparathyroidism is deficiency of parathyroid hormone (PTH) which resulting in hypocalsemia and hyperphosphatemia. It involved calcium concentration which plays a vital role in the the pathophysiology and diagnosis of hypoparathyroidism. The following diagram shows the hydroxilation of vitamin D to its active form and its action to increase the serum calcium concentration. Find sections such the roles of PTH, vitamin D and calcitonin, detaile…