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Bone Remodeling and Pathogenesis of Glucocorticoid-Induced Bone Disease

The pathophysiology of glucocorticoid-induced bone disease involve interactions with calcium and bone metabolism at multiple levels with both direct and indirect effects which impact on osteoblasts and osteoclasts. See informations about glucocorticoid-induced osteoporosis (the cellular changes, bone histomorphometry) in this journal. The balance between bone resorption, bone formation and bone cell proliferation (as seen in the picture), which…

Category: Endocrinologist, Pathophysiology | Tags: , , , | 1:33 am | comments 0 Comments

Pneumocystitis Carinii Pneumonia Life Cycle Schematic Diagram

This picture shows a schematic view of the life cycle of P.carinii, a specific pathogen for human which caused Pneumocystis pneumonia as a form of pneumonia. Two developmental stages are the mature cyst and the trophozoite. It is not yet clear which is the main infective form responsible for the primary infection. However, it is well established that airbone transmission is the most important one. Full description can be viewed here: http…

Category: Pathophysiology | Tags: , , | 10:44 am | comments 1 Comment