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Pathophysiology Algorithm Diagram of Hypertensive Emergencies

Pathophysiology of hypertensive emergency (crisis hypertension) is shown in the picture below (click to enlarge image). Hypertensive emergency is characterized by a severe elevation in blood pressure (> 180/120 mm Hg) complicated by evidence of impending or progressive target organ dysfunction (coronary ischemia, disordered cerebral function, cerebrovascular events, pulmonary edema, and renal failure). …

Bone Remodeling and Pathogenesis of Glucocorticoid-Induced Bone Disease

The pathophysiology of glucocorticoid-induced bone disease involve interactions with calcium and bone metabolism at multiple levels with both direct and indirect effects which impact on osteoblasts and osteoclasts. See informations about glucocorticoid-induced osteoporosis (the cellular changes, bone histomorphometry) in this journal. The balance between bone resorption, bone formation and bone cell proliferation (as seen in the picture), which…