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The Pathogenesis and Treatment of the Coagulopathy of Sepsis

ent cell surfaces in three overlapping phases. There are: Initiation, …takes place on tissue factor-bearing cells. Once a sufficiently strong procoagulant stimulus is generated, enough factors Xa, IXa and thrombin are formed to initiate the coagulation process…      2.  Amplification, …as platelets adhere to the initiation site, they become activated and accumulate co-factors on their surfaces amplify…

Category: Internist, Pathophysiology | Tags: , , | 10:16 am | comments 0 Comments

Serum Calcium Concentration in the Pathophysiology of Hypoparathyroidism

hypoparathyroidism-pathophysiology-diagram_thumb.png

Hypoparathyroidism is deficiency of parathyroid hormone (PTH) which resulting in hypocalsemia and hyperphosphatemia. It involved calcium concentration which plays a vital role in the the pathophysiology and diagnosis of hypoparathyroidism. The following diagram shows the hydroxilation of vitamin D to its active form and its action to increase the serum calcium concentration. Find sections such the roles of PTH, vitamin D and calcitonin, detaile…

Category: Endocrinologist, Pathophysiology | Tags: , , | 11:23 pm | comments 1 Comment