An immune-mediated disease that predominantly affects the skin and joints is the definition of psoriasis. People with psoriasis may also have Psoriatic Arthritis, and this guideline provides recommendations in the diagnosis and management of psoriasis and psoriatic arthritis. Since this psoriasis guideline covers early diagnosis of Psoriatic Arthritis, Screening of Comorbidities, Assessment of Disease Severity, Non-pharmacological Treatme…
Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured. Sections such Clinical associations, Pathophysiol…
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