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Bone Remodeling and Pathogenesis of Glucocorticoid-Induced Bone Disease

The pathophysiology of glucocorticoid-induced bone disease involve interactions with calcium and bone metabolism at multiple levels with both direct and indirect effects which impact on osteoblasts and osteoclasts. See informations about glucocorticoid-induced osteoporosis (the cellular changes, bone histomorphometry) in this journal. The balance between bone resorption, bone formation and bone cell proliferation (as seen in the picture), which…

Category: Endocrinologist, Pathophysiology | Tags: , , , | 1:33 am | comments 0 Comments

The Differentiation Pathway Diagram of Osteoblasts in Bone Remodeling

The differentiation pathway for osteoblasts in the bone remodeling cycle is illustrated in the following diagram. You may read the full article for Pathway Diagram of Osteoblasts and see more about Interaction of hematopoietic and stromal cells, Systemic Regulation of Bone Remodeling, Local Regulators of Bone Remodeling, Pathways by which estrogen may alter local factors may influence, the Pathophysiology of Bone Remodeling and disorders related…

Category: Pathophysiology | Tags: , , , | 10:16 am | comments 0 Comments