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Cushing’s Syndrome Pathophysiology Diagram and Guideline

negative feedback servo mechanism diagram of Cushing's Syndrome

Cushing’s Syndrome (hypercortisolism) is hormonal disorder caused by prolonged exposure of the body’s tissues to high levels of the hormone cortisol which can be from both serum ACTH low (iatrogenic, adrenal neoplasm) and serum ACTH high (pituitary neoplasm, ectopic ACTH). The pathophysiology diagram of Cushing’s Syndrome can be understood through the above illustration, since the outcome of this cycle is people develop Cushing’s syndrome becau…

Pathophysiology Algorithm Diagram of Hypertensive Emergencies

Pathophysiology of hypertensive emergency (crisis hypertension) is shown in the picture below (click to enlarge image). Hypertensive emergency is characterized by a severe elevation in blood pressure (> 180/120 mm Hg) complicated by evidence of impending or progressive target organ dysfunction (coronary ischemia, disordered cerebral function, cerebrovascular events, pulmonary edema, and renal failure). …