Malaria is a very old disease originating in Africa, spreading as humankind migrated to other lands. The disease gets its name from an Italian word for “bad air”. If we need to investigate the progress of malaria, we should consider the relationships between human and Anopheles mosquito populations, since both are necessary for the life cycle of Plasmodium.
The diagram shows the life cycle of Plasmodium falciparum - the deadliest of all the human malarias. It covers the explanation of one species of female Anopheline mosquitoes which can host malaria-causing Plasmodium from sporozoites into her human host, multiplying asexually to produce thousands of merozoites, merozoites maturity into male and female gametocytes, until the female mosquito takes her blood meal again resulting oocyst that divides to produce thousands of sporozoites which will migrate to the salivary glands of the mosquito into a human host, again.