Rheumatoid Arthritis (RA) is a chronic, progressive, systemic inflamatory disorder which affecting the synovial joints 
and can lead to joint destruction. The herein diagram shows the mechanisms involved in Rheumatoid Arthritis pathogenesis.
The pathogenesis of Rheumatoid Arthritis diagram includes key factors such Human Leucocyte Antigen (HLA), Intercellular Adhesion Molecule (ICAM), Interferon (IFN), Interleukin (IL), T-cell involved with cell-mediated response (Th1), Vascular Cell Adhesion Molecule (VCAM), and Tumour Necrosis Factor (TNF).
See sections such prevalence of RA, the aetiology, histological changes, cellular infiltration, the immune response, pathogenesis of bone disease, and the role of cytokines in The Mechanisms Involved in Rheumatoid Arthritis Pathogenesis of pdf filetype (source: pharmj.com)
