A flow diagram which performed the relation between Sodium Hydrogen (Na+/H+) exchanger activation and essential hypertension is shown in the 
following picture. According to a journal, an increased Na+/H+ exchanger could play a significant role in the pathogenesis of hypertension.
The mechanism related to the pathogenesis of hypertension is both by stimulating vascular tone and cell growth and possibly by increasing sodium reabsorption in renal proximal tubule cells.
