Pancreatitis due to alcohol abuse is a very painful and potentially fatal condition. The following article reported the 
mechanisms of alcohol activating of signal transduction pathways related to the pathophysiology of chronic alcoholic pancreatitis.
You’ll be described with oxidative and a non-oxidative pathway of the alcohol metabolism, genetic predisposition of acute and chronic pancreatitis, stimulatory effect on gastric acid secretion of ethanol, the mechanism of ethanol induced pancreatic injury, cigarette smoking and pancreatitis, and effect of alcohol on cell signalling pathway.
Read more complete about Pathophysiology of Chronic Alcoholic Pancreatitis : http://www.wjgnet.com/1007-9327/12/7421.pdf
