Archive for the ‘Pathophysiology’ Category

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The Differentiation Pathway Diagram of Osteoblasts in Bone Remodeling

The differentiation pathway for osteoblasts in the bone remodeling cycle is illustrated in the following diagram.

A Physiopathological Mechanism for Postmenopausal Bone Loss in Osteoporotic Women

A study which evaluated a possibilities increase in spontaneous osteoclast formation in postmenopausal osteoporotic women is described below. The schematic diagram demonstrates an increase in the production of RANKL and TNF-A by PBMC of osteoporotic women with respect to controls.