The following schematic diagram illustrates Blood Glucose Negative Feedback in the terms of rises and falls of blood glucose levels into normal levels.

The Blood Glucose Negative Feedback involved components such Islet beta cell of pancreas, Insulin, glucagon, fat/adipose cells with glycerol and fatty acids, liver cells, and the turnover of glucose and glycogen.
Herein algorithm guideline shows Type 2 Diabetes Glycemic Treatment adapted from Diabetes Care 2008. It may help physicians for the treatment of hyperglycemia in patients with type 2 diabetes as a recommended pathway for treating hyperglycemia.

The algorithm diagram encourages rapidly adding additional therapy if the patient does not achieve A1C goal, accordingly.
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