Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured.
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You may find issues related to the lens metabolism such senile cataract, Mechanisms Involved in the Pathophysiology of Cataracts, Metabolism of Hydrogen Peroxide by Glutathione, Dietary Factors in Cataract Risk, Diabetic (Sugar) Cataracts, The Polyol Pathway Diagram, The Aldose Reductase Inhibitor Activity of Some Flavonoids, Glutathione in Diabetic Cataracts, and Chronic Open-Angle Glaucoma.
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Guillain Barre’ Syndrom (GBS) is a rare autoimmune disease and the most common cause of acute flaccid paralysis in adults and children in the United States. The following document will help primary care physicians/practitioners about GBS and the importance of its recognition in the acute care setting which may increase awareness of the physicians in the diagnosis and treatment of GBS.
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