Physician Guideline | Pathophysiology Diagram | Job Vacancies

The pathophysiology of HIV infection plays an important role on how the virus attack the immune system and performed a clinical illness, explains the dynamics of viral reproduction, and finally explains where and how antiviral agents work.

[Read more →]

Hypoparathyroidism is deficiency of parathyroid hormone (PTH) which resulting in hypocalsemia and hyperphosphatemia. It involved calcium concentration which plays a vital role in the the pathophysiology and diagnosis of hypoparathyroidism. The following diagram shows the hydroxilation of vitamin D to its active form and its action to increase the serum calcium concentration.

[Read more →]

Aplastic anemia is an immune-mediated disease where bone marrow does not produce sufficient new cells to replenish blood cells in the paradigm of the human bone marrow failure syndroms (wikipedia). Hematopoietic stem-cell compartment is the target for the immune response in the pathophysiology concept of Aplastic anemia. The following figure shows the immune destruction of hematopoiesis occured.

[Read more →]